diff --git a/extensions/voice-call/src/webhook-security.test.ts b/extensions/voice-call/src/webhook-security.test.ts
index a80af69b605..3134f18b729 100644
--- a/extensions/voice-call/src/webhook-security.test.ts
+++ b/extensions/voice-call/src/webhook-security.test.ts
@@ -605,7 +605,6 @@ describe("verifyTwilioWebhook", () => {
     expect(result.ok).toBe(false);
     expect(result.verificationUrl).toBe("https://legitimate.example.com/voice/webhook");
   });
-
   it("returns a stable request key when verification is skipped", () => {
     const ctx = {
       headers: {},
@@ -621,4 +620,32 @@ describe("verifyTwilioWebhook", () => {
     expect(second.verifiedRequestKey).toBe(first.verifiedRequestKey);
     expect(second.isReplay).toBe(true);
   });
+
+  it("succeeds when Twilio signs URL without port but server URL has port", () => {
+    const authToken = "test-auth-token";
+    const postBody = "CallSid=CS123&CallStatus=completed&From=%2B15550000000";
+    // Twilio signs using URL without port.
+    const urlWithPort = "https://example.com:8443/voice/webhook";
+    const signedUrl = "https://example.com/voice/webhook";
+
+    const signature = twilioSignature({ authToken, url: signedUrl, postBody });
+
+    const result = verifyTwilioWebhook(
+      {
+        headers: {
+          host: "example.com:8443",
+          "x-twilio-signature": signature,
+        },
+        rawBody: postBody,
+        url: urlWithPort,
+        method: "POST",
+      },
+      authToken,
+      { publicUrl: urlWithPort },
+    );
+
+    expect(result.ok).toBe(true);
+    expect(result.verificationUrl).toBe(signedUrl);
+    expect(result.verifiedRequestKey).toMatch(/^twilio:req:/);
+  });
 });
diff --git a/extensions/voice-call/src/webhook-security.ts b/extensions/voice-call/src/webhook-security.ts
index 75d1ca490d0..6267e21dfc0 100644
--- a/extensions/voice-call/src/webhook-security.ts
+++ b/extensions/voice-call/src/webhook-security.ts
@@ -379,6 +379,41 @@ function isLoopbackAddress(address?: string): boolean {
   return false;
 }
 
+function stripPortFromUrl(url: string): string {
+  try {
+    const parsed = new URL(url);
+    if (!parsed.port) {
+      return url;
+    }
+    parsed.port = "";
+    return parsed.toString();
+  } catch {
+    return url;
+  }
+}
+
+function setPortOnUrl(url: string, port: string): string {
+  try {
+    const parsed = new URL(url);
+    parsed.port = port;
+    return parsed.toString();
+  } catch {
+    return url;
+  }
+}
+
+function extractPortFromHostHeader(hostHeader?: string): string | undefined {
+  if (!hostHeader) {
+    return undefined;
+  }
+  try {
+    const parsed = new URL(`https://${hostHeader}`);
+    return parsed.port || undefined;
+  } catch {
+    return undefined;
+  }
+}
+
 /**
  * Result of Twilio webhook verification with detailed info.
  */
@@ -609,6 +644,45 @@ export function verifyTwilioWebhook(
     return { ok: true, verificationUrl, isReplay, verifiedRequestKey: replayKey };
   }
 
+  // Twilio webhook signatures can differ in whether port is included.
+  // Retry a small, deterministic set of URL variants before failing closed.
+  const variants = new Set<string>();
+  variants.add(verificationUrl);
+  variants.add(stripPortFromUrl(verificationUrl));
+
+  if (options?.publicUrl) {
+    try {
+      const publicPort = new URL(options.publicUrl).port;
+      if (publicPort) {
+        variants.add(setPortOnUrl(verificationUrl, publicPort));
+      }
+    } catch {
+      // ignore invalid publicUrl; primary verification already used best effort
+    }
+  }
+
+  const hostHeaderPort = extractPortFromHostHeader(getHeader(ctx.headers, "host"));
+  if (hostHeaderPort) {
+    variants.add(setPortOnUrl(verificationUrl, hostHeaderPort));
+  }
+
+  for (const candidateUrl of variants) {
+    if (candidateUrl === verificationUrl) {
+      continue;
+    }
+    const isValidCandidate = validateTwilioSignature(authToken, signature, candidateUrl, params);
+    if (!isValidCandidate) {
+      continue;
+    }
+    const replayKey = createTwilioReplayKey({
+      verificationUrl: candidateUrl,
+      signature,
+      requestParams: params,
+    });
+    const isReplay = markReplay(twilioReplayCache, replayKey);
+    return { ok: true, verificationUrl: candidateUrl, isReplay, verifiedRequestKey: replayKey };
+  }
+
   // Check if this is ngrok free tier - the URL might have different format
   const isNgrokFreeTier =
     verificationUrl.includes(".ngrok-free.app") || verificationUrl.includes(".ngrok.io");