diff --git a/extensions/matrix/src/matrix/monitor/handler.strip-mention.test.ts b/extensions/matrix/src/matrix/monitor/handler.strip-mention.test.ts
new file mode 100644
index 00000000000..823b329f5cf
--- /dev/null
+++ b/extensions/matrix/src/matrix/monitor/handler.strip-mention.test.ts
@@ -0,0 +1,105 @@
+import { describe, expect, it } from "vitest";
+
+/**
+ * Test helper to strip mention prefixes from text for slash command detection.
+ * This is the test for the fix of issue #68547.
+ */
+function stripMatrixMentionPrefixes(text: string, mentionRegexes: RegExp[]): string {
+  if (!text || mentionRegexes.length === 0) {
+    return text;
+  }
+  let result = text;
+  for (const pattern of mentionRegexes) {
+    // Match mention at the start of the text, followed by optional whitespace
+    const match = result.match(new RegExp(`^(${pattern.source})\\s*`));
+    if (match) {
+      result = result.slice(match[0].length).trimStart();
+      break; // Only strip the first mention prefix
+    }
+  }
+  return result;
+}
+
+describe("stripMatrixMentionPrefixes", () => {
+  it("returns original text when mentionRegexes is empty", () => {
+    const text = "@bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, []);
+    expect(result).toBe("@bot:server /new");
+  });
+
+  it("returns original text when text is empty", () => {
+    const result = stripMatrixMentionPrefixes("", [/\s*@bot:server\s*/]);
+    expect(result).toBe("");
+  });
+
+  it("strips mention prefix before slash command (issue #68547)", () => {
+    const mentionRegexes = [/@bot:server\b/];
+    const text = "@bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("/new");
+  });
+
+  it("strips mention prefix with extra whitespace", () => {
+    const mentionRegexes = [/@bot:server\b/];
+    const text = "@bot:server   /help";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("/help");
+  });
+
+  it("strips mention prefix with display name", () => {
+    const mentionRegexes = [/@OpenClaw Bot\b/];
+    const text = "@OpenClaw Bot /model";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("/model");
+  });
+
+  it("does not strip mention from middle of text", () => {
+    const mentionRegexes = [/@bot:server\b/];
+    const text = "Hello @bot:server how are you";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("Hello @bot:server how are you");
+  });
+
+  it("does not strip non-matching patterns", () => {
+    const mentionRegexes = [/@otherbot:server\b/];
+    const text = "@bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("@bot:server /new");
+  });
+
+  it("strips only the first mention prefix", () => {
+    const mentionRegexes = [/@bot:server\b/];
+    const text = "@bot:server @bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("@bot:server /new");
+  });
+
+  it("handles multiple regex patterns and strips first match", () => {
+    const mentionRegexes = [/@otherbot:server\b/, /@bot:server\b/];
+    const text = "@bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    // First pattern doesn't match, second does
+    expect(result).toBe("/new");
+  });
+
+  it("preserves original text when no patterns match", () => {
+    const mentionRegexes = [/@otherbot:server\b/, /@anotherbot:server\b/];
+    const text = "@bot:server /new";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("@bot:server /new");
+  });
+
+  it("handles regex with special characters in mention", () => {
+    const mentionRegexes = [/@bot\+123:server\.com\b/];
+    const text = "@bot+123:server.com /status";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("/status");
+  });
+
+  it("preserves regular message without slash command after stripping", () => {
+    const mentionRegexes = [/@bot:server\b/];
+    const text = "@bot:server hello world";
+    const result = stripMatrixMentionPrefixes(text, mentionRegexes);
+    expect(result).toBe("hello world");
+  });
+});
diff --git a/extensions/matrix/src/matrix/monitor/handler.ts b/extensions/matrix/src/matrix/monitor/handler.ts
index 57792075810..94a770fbe70 100644
--- a/extensions/matrix/src/matrix/monitor/handler.ts
+++ b/extensions/matrix/src/matrix/monitor/handler.ts
@@ -268,6 +268,27 @@ function resolveMatrixMentionPrecheckText(params: {
   return "";
 }
 
+/**
+ * Strip mention prefixes from text for slash command detection.
+ * This ensures that messages like "@bot:server /new" are recognized as slash commands.
+ * Similar to Feishu's normalizeMentions and Mattermost's stripMentionPrefix.
+ */
+function stripMatrixMentionPrefixes(text: string, mentionRegexes: RegExp[]): string {
+  if (!text || mentionRegexes.length === 0) {
+    return text;
+  }
+  let result = text;
+  for (const pattern of mentionRegexes) {
+    // Match mention at the start of the text, followed by optional whitespace
+    const match = result.match(new RegExp(`^(${pattern.source})\\s*`));
+    if (match) {
+      result = result.slice(match[0].length).trimStart();
+      break; // Only strip the first mention prefix
+    }
+  }
+  return result;
+}
+
 function hasBundledMatrixReplacementRelation(event: MatrixRawEvent) {
   const relations = event.unsigned?.["m.relations"];
   if (!relations || typeof relations !== "object") {
@@ -935,8 +956,14 @@ export function createMatrixRoomMessageHandler(params: MatrixMonitorHandlerParam
           surface: "matrix",
         });
         const useAccessGroups = cfg.commands?.useAccessGroups !== false;
-        const hasControlCommandInMessage = core.channel.text.hasControlCommand(
+        // Strip mention prefixes before checking for slash commands so that messages
+        // like "@bot:server /new" are recognized as slash commands (#68547)
+        const commandCheckText = stripMatrixMentionPrefixes(
           mentionPrecheckText,
+          agentMentionRegexes,
+        );
+        const hasControlCommandInMessage = core.channel.text.hasControlCommand(
+          commandCheckText,
           cfg,
         );
         const commandGate = resolveControlCommandGate({